General Info
| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human/Pig/Rhesus/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-CD32 is suitable for use in Flow Cytometry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | AT10 |
| Conjugation: | Biotin |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.09% sodium azide and 1% BSA |
| Concentration: | 0.1 mg/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
Information
| Gene Symbol: | FCGR2A |
| Gene ID: | 2212 |
| Uniprot ID: | FCG2A_HUMAN |
| Immunogen: | K562 cell line. |
Description
| Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
| Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
| Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A antibodyAnti-Igg Fc Receptor Ii-A antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-A antibodyAnti-Fc-Gamma-Riia antibodyAnti-Fcrii-A antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2A antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-FCGR2A1 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance