General Info
Host: | Rabbit |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-GLUT1 is suitable for use in Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Purification: | Affinity purified |
Dilution Range: | IHC-P 1:50-1:200 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Information
Gene Symbol: | SLC2A1 |
Gene ID: | 6513 |
Uniprot ID: | GTR1_HUMAN |
Description
Tissue Specificity | Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. |
Post Translational Modifications | Phosphorylation at Ser-226 by PKC promotes glucose uptake by increasing cell membrane localization. |
Function | Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity.can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation. |
Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1Glucose Transporter Type 1 - Erythrocyte/BrainGlut-1Hepg2 Glucose Transporter |
Database Links | Reactome: R-HSA-189200Reactome: R-HSA-196836Reactome: R-HSA-422356Reactome: R-HSA-5619043Reactome: R-HSA-5653890 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMelanosomePhotoreceptor Inner SegmentLocalizes Primarily At The Cell SurfaceIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 1 antibodyAnti-Glucose Transporter Type 1 - Erythrocyte/Brain antibodyAnti-Glut-1 antibodyAnti-Hepg2 Glucose Transporter antibodyAnti-SLC2A1 antibodyAnti-GLUT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance