General Info
| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Horse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SLC2A5 (490-500) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.7 µg/µl |
| Dilution Range: | WB: 1:1, 000DB: 1:4, 000ELISA: 1:4, 000IP: 1:200IHC: 1:50-1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | SLC2A5 |
| Gene ID: | 6518 |
| Uniprot ID: | GTR5_HUMAN |
| Immunogen Region: | 490-500 |
| Specificity: | Does not react with GLUT1, 2, 3, or 4 from human, mouse or rat. |
| Immunogen: | Synthetic peptide corresponding to C terminal amino acids 490-500 of Human Glucose Transporter 5 GLUT5. A cysteine residue was included at the N-terminus of the peptide to accommodate KLH conjugation. |
Description
| Tissue Specificity | Detected in skeletal muscle, and in jejunum brush border membrane and basolateral membrane (at protein level). Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. |
| Function | Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. |
| Protein Name | Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5Fructose TransporterGlucose Transporter Type 5 - Small IntestineGlut-5 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8981373 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneSarcolemmaLocalized On The Apical Membrane Of Jejunum VilliBut Also On Lateral Plasma Membranes Of The VilliTransport To The Cell Membrane Is Dependent On Rab11a |
| Alternative Antibody Names | Anti-Solute Carrier Family 2 - Facilitated Glucose Transporter Member 5 antibodyAnti-Fructose Transporter antibodyAnti-Glucose Transporter Type 5 - Small Intestine antibodyAnti-Glut-5 antibodyAnti-SLC2A5 antibodyAnti-GLUT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance