GTX01458-11-100ug | CD3 antibody [17A2] (PerCP-Cy5.5) Clinisciences

Host	Rat
Clonality	Monoclonal
Clone Name	17A2
Isotype	IgG2b
Application	FACS
Reactivity	Mouse
Package	100 μg

Yuan J et al. Protein Cell 2021; 12 (4):240-260 Potentiating CD8⁺ T cell antitumor activity by inhibiting PCSK9 to promote LDLR-mediated TCR recycling and signaling.

Heffer AM et al. PLoS One 2020; 15 (12):e0243626 Salinomycin inhibits proliferative vitreoretinopathy formation in a mouse model.

Do MH et al. J Exp Med 2020; 217 (1) Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance.

O'Hara JM et al. Mucosal Immunol 2020; 13 (1):172-182 Generation of protective pneumococcal-specific nasal resident memory CD4⁺ T cells via parenteral immunization.

Kim HJ et al. Allergy Asthma Immunol Res 2020; 12 (1):137-148 Antibiotics-Induced Dysbiosis of Intestinal Microbiota Aggravates Atopic Dermatitis in Mice by Altered Short-Chain Fatty Acids.

Du X et al. J Exp Med 2020; 217 (2) Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.

Li F et al. Cancer Discov 2020; 10 (2):270-287 In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma.

Yuan CH et al. Scand J Immunol 2020; 91 (2):e12843 Mannose-capped lipoarabinomannan-induced B10 cells decrease severity of dextran sodium sulphate-induced inflammatory bowel disease in mice.

Erkes DA et al. Cancer Discov 2020; 10 (2):254-269 Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis.

Bellmann L et al. Int J Cancer 2020; 146 (5):1409-1420 A TLR7 agonist strengthens T and NK cell function during BRAF-targeted therapy in a preclinical melanoma model.

Janssen WJ et al. G3 (Bethesda) 2020; 10 (2):555-567 Inflammation-Induced Alternative Pre-mRNA Splicing in Mouse Alveolar Macrophages.

Uribe-Herranz M et al. J Clin Invest 2020; 130 (1):466-479 Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response.

Meyer M et al. J Cell Mol Med 2020; 24 (2):1774-1785 Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes.

Zhou Q et al. EMBO Mol Med 2020; 12 (2):e10919 Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.

Bliss CM et al. Mol Ther Methods Clin Dev 2020; 16:108-125 Targeting Antigen to the Surface of EVs Improves the In?Vivo Immunogenicity of Human and Non-human Adenoviral Vaccines in Mice.

Fachi JL et al. J Exp Med 2020; 217 (3) Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2.

Szade K et al. EMBO Rep 2020; 21 (2):e47895 Heme oxygenase-1 deficiency triggers exhaustion of hematopoietic stem cells.

Zhang X et al. J Cancer 2020; 11 (3):648-656 Increased Tim-3 expression on TILs during treatment with the Anchored GM-CSF vaccine and anti-PD-1 antibodies is inversely correlated with response in prostate cancer.

Tarumoto Y et al. Blood 2020; 135 (1):56-70 Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo.

Oyesola OO et al. J Immunol 2020; 204 (4):1001-1011 The Prostaglandin D₂ Receptor CRTH2 Promotes IL-33-Induced ILC2 Accumulation in the Lung.

Chrisikos TT et al. Cancers (Basel) 2020; 12 (1) STAT3 Inhibits CD103⁺ cDC1 Vaccine Efficacy in Murine Breast Cancer.

Hidalgo San Jose L et al. Cell Rep 2020; 30 (1):69-80.e6 Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.

Regan-Komito D et al. Nat Commun 2020; 11 (1):155 GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis.

Aegerter H et al. Nat Immunol 2020; 21 (2):145-157 Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.

Suresh R et al. J Immunother Cancer 2020; 8 (1) NF-κB p50-deficient immature myeloid cell (p50-IMC) adoptive transfer slows the growth of murine prostate and pancreatic ductal carcinoma.

Lynn GM et al. Nat Biotechnol 2020; 38 (3):320-332 Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens.

Rohner L et al. Sci Rep 2020; 10 (1):222 Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study.

Schafflick D et al. Nat Commun 2020; 11 (1):247 Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis.

Rosenbaum SR et al. Cell Rep 2020; 30 (2):510-524.e6 FOXD3 Regulates VISTA Expression in Melanoma.

Akula S et al. Cells 2020; 9 (1) Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity.

Chen J et al. Sci Adv 2020; 6 (3):eaay8230 Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists.

Baxter VK et al. Viruses 2020; 12 (1) Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis.

Busbee PB et al. JCI Insight 2020; 5 (1) Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.

Martin-Ruiz C et al. NPJ Aging Mech Dis 2020; 6:3 CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians.

Yu M et al. Nat Commun 2020; 11 (1):468 PTH induces bone loss via microbial-dependent expansion of intestinal TNF⁺ T cells and Th17 cells.

Kirsebom F et al. Sci Rep 2020; 10 (1):1110 Neutrophils do not impact viral load or the peak of disease severity during RSV infection.

Sadler R et al. J Neurosci 2020; 40 (5):1162-1173 Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.

Chen H et al. Sci Adv 2020; 6 (5):eaax4690 Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9⁺ T cells.

Li Y et al. Nat Commun 2020; 11 (1):581 Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice.

Darling TK et al. PLoS Pathog 2020; 16 (1):e1008261 EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.

Sharma M et al. Nat Commun 2020; 11 (1):661 Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy.

Shao G et al. J Inflamm (Lond) 2020; 17:3 Dendritic cells transduced with glioma-expressed antigen 2 recombinant adenovirus induces specific cytotoxic lymphocyte response and anti-tumor effect in mice.

Delconte RB et al. Front Immunol 2020; 11:75 NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS.

Webster HC et al. J Immunol Methods 2020; 477:112702 Isolation and functional characterisation of lamina propria leukocytes from helminth-infected, murine small intestine.

Fu D et al. Am J Cancer Res 2020; 10 (2):473-490 T cell recruitment triggered by optimal dose platinum compounds contributes to the therapeutic efficacy of sequential PD-1 blockade in a mouse model of colon cancer.

Ramalingam P et al. Nat Commun 2020; 11 (1):666 Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF.

Olender L et al. Sci Rep 2020; 10 (1):1812 Cyclosporine H Improves the Multi-Vector Lentiviral Transduction of Murine Haematopoietic Progenitors and Stem Cells.

Cohen G et al. Cancers (Basel) 2020; 12 (2) The Impact of Focused Ultrasound in Two Tumor Models: Temporal Alterations in the Natural History on Tumor Microenvironment and Immune Cell Response.

Koliesnik IO et al. Front Immunol 2020; 11:132 The Heparan Sulfate Mimetic PG545 Modulates T Cell Responses and Prevents Delayed-Type Hypersensitivity.

Kunishita Y et al. Front Immunol 2020; 11:98 TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis.

Tan Z et al. Mol Ther Oncolytics 2020; 16:302-317 Antimesothelioma Immunotherapy by CTLA-4 Blockade Depends on Active PD1-Based TWIST1 Vaccination.

Ferrer-Font L et al. Elife 2020; 9 High-dimensional analysis of intestinal immune cells during helminth infection.

Ferreira SS et al. Front Immunol 2020; 11:84 Insulin Modulates the Immune Cell Phenotype in Pulmonary Allergic Inflammation and Increases Pulmonary Resistance in Diabetic Mice.

Yamazaki T et al. Oncoimmunology 2020; 9 (1):1721810 PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models.

Robichon K et al. J Neuroinflammation 2020; 17 (1):53 Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis.

Galvani E et al. Nat Commun 2020; 11 (1):853 Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.

Abadie V et al. Nature 2020; 578 (7796):600-604 IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease.

Treat BR et al. J Virol 2020; 94 (5) Herpes Simplex Virus 1-Specific CD8⁺ T Cell Priming and Latent Ganglionic Retention Are Shaped by Viral Epitope Promoter Kinetics.

Kindermann M et al. Front Immunol 2020; 11:209 Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis.

Huang TY et al. Front Chem 2020; 8:1 Supramolecular Photothermal Nanomedicine Mediated Distant Tumor Inhibition via PD-1 and TIM-3 Blockage.

Spidale NA et al. Elife 2020; 9 Neonatal-derived IL-17 producing dermal γδ T cells are required to prevent spontaneous atopic dermatitis.

Wang H et al. Nat Immunol 2020; 21 (3):298-308 CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.

Moyer TJ et al. Nat Med 2020; 26 (3):430-440 Engineered immunogen binding to alum adjuvant enhances humoral immunity.

Hu B et al. Nature 2020; 578 (7796):610-614 γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis.

Moral JA et al. Nature 2020; 579 (7797):130-135 ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity.

Fu Y et al. Sci Adv 2020; 6 (9):eaay9269 Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2.

Petrova T et al. Sci Rep 2020; 10 (1):3479 p38 MAPK signalling regulates cytokine production in IL-33 stimulated Type 2 Innate Lymphoid cells.

Salomonsson M et al. Front Immunol 2020; 11:321 Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors.

Martinez-Usatorre A et al. Front Immunol 2020; 11:340 Enhanced Phenotype Definition for Precision Isolation of Precursor Exhausted Tumor-Infiltrating CD8 T Cells.

Tseng SH et al. J Immunother Cancer 2020; 8 (1) Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis.

Yu X et al. Nat Commun 2020; 11 (1):1110 Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response.

Martens R et al. Nat Commun 2020; 11 (1):1114 Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance.

Ogita T et al. Front Immunol 2020; 11:379 Oral Administration of Flavonifractor plautii Strongly Suppresses Th2 Immune Responses in Mice.

Zaid A et al. mBio 2020; 11 (2) Modulation of Monocyte-Driven Myositis in Alphavirus Infection Reveals a Role for CX₃CR1⁺ Macrophages in Tissue Repair.

Zhang W et al. Nat Commun 2020; 11 (1):1187 Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy.

Chao Y et al. Sci Adv 2020; 6 (10):eaaz4204 Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses.

Zang M et al. Oncogenesis 2020; 9 (3):31 Cdc37 suppression induces plasma cell immaturation and bortezomib resistance in multiple myeloma via Xbp1s.

Doll JR et al. PLoS Pathog 2020; 16 (3):e1008296 Resolution of herpes simplex virus reactivation in vivo results in neuronal destruction.

Abeyratne E et al. Front Immunol 2020; 11:304 Liposomal Delivery of the RNA Genome of a Live-Attenuated Chikungunya Virus Vaccine Candidate Provides Local, but Not Systemic Protection After One Dose.

Loffredo LF et al. Sci Rep 2020; 10 (1):4425 Eosinophil accumulation in postnatal lung is specific to the primary septation phase of development.

Han P et al. Sci Adv 2020; 6 (11):eaaz1580 Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.

Honda M et al. Nat Commun 2020; 11 (1):1329 Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome.

Wang G et al. Nat Commun 2020; 11 (1):1395 An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses.

Wuggenig P et al. Commun Biol 2020; 3 (1):130 Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice.

von Roemeling CA et al. Nat Commun 2020; 11 (1):1508 Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.

Song E et al. Nature 2020; 577 (7792):689-694 VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours.

Zuo H et al. Nat Commun 2020; 11 (1):1578 Differential regulation of breast cancer bone metastasis by PARP1 and PARP2.

Rouse MD et al. Front Microbiol 2020; 11:414 Impact of Frequent Administration of Bacteriophage on Therapeutic Efficacy in an A. baumannii Mouse Wound Infection Model.

Celik M? et al. JCI Insight 2020; 5 (4) IL-4 induces M2 macrophages to produce sustained analgesia via opioids.

David P et al. PLoS Pathog 2020; 16 (3):e1008340 Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

Ghouse SM et al. Front Oncol 2020; 10:384 Oncolytic Herpes Simplex Virus Encoding IL12 Controls Triple-Negative Breast Cancer Growth and Metastasis.

Iglesias-Guimarais V et al. J Immunol 2020; 204 (8):2110-2121 IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell-Dependent Route.

Sacramento LA et al. PLoS Pathog 2020; 16 (3):e1008435 TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection.

Chen G et al. BMC Infect Dis 2020; 20 (1):266 Plasmodium yoelii 17XL infection modified maturation and function of dendritic cells by skewing Tregs and amplificating Th17.

Nelson AS et al. Sci Rep 2020; 10 (1):6156 Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice.

Lu DR et al. Life Sci Alliance 2020; 3 (5) Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein.

Han Y et al. Nat Commun 2020; 11 (1):1776 Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma.

Goda C et al. PLoS Genet 2020; 16 (4):e1008692 Loss of FOXM1 in macrophages promotes pulmonary fibrosis by activating p38 MAPK signaling pathway.

de Melo CVB et al. Front Immunol 2020; 11:653 Phenotypical Characterization of Spleen Remodeling in Murine Experimental Visceral Leishmaniasis.

Sznajder ?J et al. Nat Commun 2020; 11 (1):2022 Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood.

Waaler J et al. Commun Biol 2020; 3 (1):196 Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.

Burfeind KG et al. Glia 2020; 68 (7):1479-1494 Microglia in the hypothalamus respond to tumor-derived factors and are protective against cachexia during pancreatic cancer.

Ma Z et al. Front Immunol 2020; 11:687 Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice.

Zebertavage LK et al. Sci Rep 2020; 10 (1):7376 Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity.

Bosteels C et al. Immunity 2020; 52 (6):1039-1056.e9 Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.

Humeau J et al. EMBO Mol Med 2020; 12 (5):e11622 Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.

Rossi A et al. Cells 2020; 9 (4) Tumor-Intrinsic or Drug-Induced Immunogenicity Dictates the Therapeutic Success of the PD1/PDL Axis Blockade.

Park SJ et al. mBio 2020; 11 (3) Herpesvirus Entry Mediator Binding Partners Mediate Immunopathogenesis of Ocular Herpes Simplex Virus 1 Infection.

Chan YH et al. Front Immunol 2020; 11:894 Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection.

Smith EC et al. PLoS One 2020; 15 (5):e0232234 Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge.

Abdissa K et al. Virulence 2020; 11 (1):465-481 Relevance of inducible nitric oxide synthase for immune control of Mycobacterium avium subspecies paratuberculosis infection in mice.

Perez LG et al. Nat Commun 2020; 11 (1):2608 TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer.

Van der Jeught K et al. JCI Insight 2020; 5 (9) ST2 as checkpoint target for colorectal cancer immunotherapy.

Burfeind KG et al. Elife 2020; 9 Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer.

Yang C et al. Elife 2020; 9 Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature.

Skirecki T et al. JCI Insight 2020; 5 (10) Bone marrow is the preferred site of memory CD4+ T cell proliferation during recovery from sepsis.

Judge SJ et al. J Clin Invest 2020; 130 (6):3051-3068 Minimal PD-1 expression in mouse and human NK cells under diverse conditions.

Owen KL et al. EMBO Rep 2020; 21 (6):e50162 Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone.

Leyva-Castillo JM et al. J Allergy Clin Immunol 2020; 145 (6):1606-1614.e4 ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation.

Moorman CD et al. J Neuroinflammation 2020; 17 (1):180 A GM-CSF-neuroantigen tolerogenic vaccine elicits inefficient antigen recognition events below the CD40L triggering threshold to expand CD4⁺ CD25⁺ FOXP3⁺ Tregs that inhibit experimental autoimmune encephalomyelitis (EAE).

Zhang H et al. BMC Biol 2020; 18 (1):64 A mutation that blocks integrin α₄β₇ activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis.

Uni R et al. Sci Rep 2020; 10 (1):9472

Riggan L et al. Cell Rep 2020; 31 (7):107651 CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Mature Primary Innate Immune Cells.

Lindner SE et al. Immunohorizons 2020; 4 (5):274-281 Arhgap25 Deficiency Leads to Decreased Numbers of Peripheral Blood B Cells and Defective Germinal Center Reactions.

Ning Y et al. J Immunother Cancer 2020; 8 (1) HDAC9 deficiency promotes tumor progression by decreasing the CD8⁺ dendritic cell infiltration of the tumor microenvironment.

Fonseca W et al. Mucosal Immunol 2020; 13 (4):691-701 Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation.

Haabeth OAW et al. Blood Adv 2020; 4 (12):2595-2605 CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages.

Svensson MND et al. Sci Adv 2020; 6 (26):eaba4353 Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.

Chiuppesi F et al. bioRxiv 2020; Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine.

Kawabe T et al. Nat Commun 2020; 11 (1):3366 Requirements for the differentiation of innate T-bet^high memory-phenotype CD4⁺ T lymphocytes under steady state.

Robbins Y et al. Elife 2020; 9 Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells.

Gajdasik DW et al. Nat Commun 2020; 11 (1):3421 Th1 responses in vivo require cell-specific provision of OX40L dictated by environmental cues.

Xu J et al. Immunity 2020; 53 (2):371-383.e5 The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.

Van Herck MA et al. Cell Mol Gastroenterol Hepatol 2020; 10 (3):467-490 Diet Reversal and Immune Modulation Show Key Role for Liver and Adipose Tissue T Cells in Murine Nonalcoholic Steatohepatitis.

Chang HF et al. Int J Mol Sci 2020; 21 (13) Investigation of Cytotoxic T Lymphocyte Function during Allorejection in the Anterior Chamber of the Eye.

Xiao Y et al. J Tissue Eng Regen Med 2020; 14 (6):884-892 High-fat diet selectively decreases bone marrow lin^- /CD117⁺ cell population in aging mice through increased ROS production.

Cai H et al. Vaccines (Basel) 2020; 8 (2) Recombinant Costimulatory Fusion Proteins as Functional Immunomodulators Enhance Antitumor Activity in Murine B16F10 Melanoma.

Iida Y et al. J Immunother Cancer 2020; 8 (2) Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells.

Alicke B et al. J Immunother Cancer 2020; 8 (2) Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge.

Clark PA et al. J Immunother Cancer 2020; 8 (2) In situ vaccination at a peripheral tumor site augments response against melanoma brain metastases.

Choi EW et al. Sci Rep 2020; 10 (1):12001 Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning.

Gleisner MA et al. J Immunother Cancer 2020; 8 (2) A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth.

Kozik P et al. Cell Rep 2020; 32 (2):107905 Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity.

Carpenter RS et al. Nat Commun 2020; 11 (1):3702 Spinal cord injury causes chronic bone marrow failure.

Ivanova DL et al. Front Cell Infect Microbiol 2020; 10:313 NK Cells Negatively Regulate CD8 T Cells to Promote Immune Exhaustion and Chronic Toxoplasma gondii Infection.

Prado MKB et al. Biomolecules 2020; 10 (6) IL-22 Promotes IFN-γ-Mediated Immunity against Histoplasma capsulatum Infection.

Mez? C et al. Acta Neuropathol Commun 2020; 8 (1):119 Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer's disease.

Fries-Craft K et al. PLoS One 2020; 15 (7):e0236106 Host immunity and the colon microbiota of mice infected with Citrobacter rodentium are beneficially modulated by lipid-soluble extract from late-cutting alfalfa in the early stages of infection.

Nettleford SK et al. Front Nutr 2020; 7:96 The Essential Role of Selenoproteins in the Resolution of Citrobacter rodentium-Induced Intestinal Inflammation.

Zou M et al. Eur J Microbiol Immunol (Bp) 2020; Acute neonatal Listeria monocytogenes infection causes long-term, organ-specific changes in immune cell subset composition.

Jazowiecka-Rakus J et al. Mol Ther Oncolytics 2020; 18:335-350 Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma.

Li KP et al. Cardiovasc Ther 2020; 2020:1389312 Recombinant Human Brain Natriuretic Peptide Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting CD4⁺ T Cell Proliferation via PI3K/AKT/mTOR Pathway Activation.

Morris AH et al. Nat Commun 2020; 11 (1):3871 Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis.

Hasegawa T et al. Sci Rep 2020; 10 (1):13480 Development of an intravital imaging system for the synovial tissue reveals the dynamics of CTLA-4 Ig in vivo.

Pasciuto E et al. Cell 2020; 182 (3):625-640.e24 Microglia Require CD4?T Cells to Complete the Fetal-to-Adult Transition.

Israelow B et al. J Exp Med 2020; 217 (12) Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.

Fernandes RA et al. Elife 2020; 9 Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo.

Johnson DC et al. Cell Death Dis 2020; 11 (8):628 DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes.

Kerkhofs D et al. Theranostics 2020; 10 (21):9512-9527 Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension.

Liu B et al. Nat Commun 2020; 11 (1):4076 An inducible circular RNA circKcnt2 inhibits ILC3 activation to facilitate colitis resolution.

Cuff AO et al. Immunology 2020; 161 (1):28-38 Tbet promotes CXCR6 expression in immature natural killer cells and natural killer cell egress from the bone marrow.

Lerbs T et al. JCI Insight 2020; 5 (16) CD47 prevents the elimination of diseased fibroblasts in scleroderma.

Pierini S et al. JCI Insight 2020; 5 (16) Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

Wang H et al. JCI Insight 2020; 5 (16) Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements.

Metwaly A et al. Nat Commun 2020; 11 (1):4322 Integrated microbiota and metabolite profiles link Crohn's disease to sulfur metabolism.

Nakazawa S et al. Sci Rep 2020; 10 (1):14559 Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading.

Poh CM et al. Front Immunol 2020; 11:400 Multiplex Screening Assay for Identifying Cytotoxic CD8⁺ T Cell Epitopes.

Alayo QA et al. Sci Rep 2020; 10 (1):5095 Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses.

Srikanthan MA et al. Mol Ther Methods Clin Dev 2020; 17:455-464 Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning.

Georganaki M et al. Oncoimmunology 2020; 9 (1):1730538 Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.

Helble JD et al. mBio 2020; 11 (2) Gamma Interferon Is Required for Chlamydia Clearance but Is Dispensable for T Cell Homing to the Genital Tract.

do Valle Duraes F et al. JCI Insight 2020; 5 (3) Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis.

Bajad P et al. Nucleic Acids Res 2020; 48 (6):3286-3303 An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.

Luo X et al. J Clin Invest 2020; 130 (4):1635-1652 HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING.

Gan H et al. Sci Adv 2020; 6 (14):eaay2793 B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response.

Si Y et al. Sci Adv 2020; 6 (14):eaaw7713 Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination.

Odak I et al. PLoS One 2020; 15 (4):e0231222 Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD.

Eskiocak U et al. JCI Insight 2020; 5 (5) Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.

Mart?nez-Blanco M et al. Nutrients 2020; 12 (3) Ovalbumin-Derived Peptides Activate Retinoic Acid Signalling Pathways and Induce Regulatory Responses Through Toll-Like Receptor Interactions.

Rosser EC et al. Cell Metab 2020; 31 (4):837-851.e10 Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.

Peng Z et al. Pathogens 2020; 9 (2) Immunization with a Bacterial Lipoprotein Establishes an Immuno-Protective Response with Upregulation of Effector CD4+ T Cells and Neutrophils Against Methicillin-Resistant Staphylococcus aureus Infection.

Chen J et al. Nat Commun 2020; 11 (1):1913 TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response.

Williams GP et al. Acta Neuropathol 2020; 139 (5):855-874 T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease.

Zheng DW et al. Nat Commun 2020; 11 (1):1985 A vaccine-based nanosystem for initiating innate immunity and improving tumor immunotherapy.

Gilfillan CB et al. Eur J Immunol 2020; 50 (4):505-514 Murine CD8 T-cell functional avidity is stable in vivo but not in vitro: Independence from homologous prime/boost time interval and antigen density.

Song M et al. Oncoimmunology 2020; 9 (1):1746148 Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response.

Baumann D et al. Nat Commun 2020; 11 (1):2176 Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy.

Bittner-Eddy PD et al. Front Immunol 2020; 11:677 Transient Expression of IL-17A in Foxp3 Fate-Tracked Cells in Porphyromonas gingivalis-Mediated Oral Dysbiosis.

Bost P et al. Cell 2020; 181 (7):1475-1488.e12 Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients.

Lawenius L et al. Am J Physiol Endocrinol Metab 2020; 318 (4):E480-E491 Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss.

Becerril-Garc?a MA et al. Front Immunol 2020; 11:744 Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo.

Minute L et al. J Immunother Cancer 2020; 8 (1) Cellular cytotoxicity is a form of immunogenic cell death.

Liu W et al. Mol Ther Oncolytics 2020; 17:350-360 In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-2.

O'Huallachain M et al. Commun Biol 2020; 3 (1):213 Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis.

Barr AM et al. Cancer Immunol Immunother 2020; Therapeutic ISCOMATRIX? adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer.

Tsukui H et al. BMC Cancer 2020; 20 (1):411 CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model.

Wachowska M et al. Cancer Immunol Immunother 2020; 69 (6):1101-1112 Inhibition of IDO leads to IL-6-dependent systemic inflammation in mice when combined with photodynamic therapy.

Dong X et al. Sci Adv 2020; 6 (20):eaba1590 Bioinorganic hybrid bacteriophage for modulation of intestinal microbiota to remodel tumor-immune microenvironment against colorectal cancer.

Bekeschus S et al. Adv Sci (Weinh) 2020; 7 (10):1903438 Medical Gas Plasma Jet Technology Targets Murine Melanoma in an Immunogenic Fashion.

Yeh CL et al. Nutrients 2020; 12 (4) Intravenous Arginine Administration Benefits CD4⁺ T-Cell Homeostasis and Attenuates Liver Inflammation in Mice with Polymicrobial Sepsis.

Chauveau A et al. Immunity 2020; 52 (5):794-807.e7 Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones.

Winchell CG et al. Front Immunol 2020; 11:891 Evaluation of IL-1 Blockade as an Adjunct to Linezolid Therapy for Tuberculosis in Mice and Macaques.

Wang F et al. Sci Adv 2020; 6 (18):eaaz8985 Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker-based immunotherapy.

van Tilburg Bernardes E et al. Nat Commun 2020; 11 (1):2577 Intestinal fungi are causally implicated in microbiome assembly and immune development in mice.

Murata A et al. Front Immunol 2020; 11:775 CD4⁺ Resident Memory T Cells Mediate Long-Term Local Skin Immune Memory of Contact Hypersensitivity in BALB/c Mice.

Ruscetti M et al. Cell 2020; 181 (2):424-441.e21 Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.

Aquino RS et al. PLoS Pathog 2020; 16 (5):e1008497 Host syndecan-1 promotes listeriosis by inhibiting intravascular neutrophil extracellular traps.

Lei N et al. Emerg Microbes Infect 2020; 9 (1):976-987 IFITM3 affects the level of antibody response after influenza vaccination.

Joffre J et al. J Immunol 2020; 204 (12):3339-3350 Activation of CB₁R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells?and Reduces Acute Inflammation and Organ Injury.

Reches A et al. J Immunother Cancer 2020; 8 (1) Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity.

Klarquist J et al. Immunohorizons 2020; 4 (3):140-152 Type I IFN Drives Experimental Systemic Lupus Erythematosus by Distinct Mechanisms in CD4 T Cells and B Cells.

He Q et al. J Mol Cell Biol 2020; 12 (5):359-371 Isoform-specific involvement of Brpf1 in expansion of adult hematopoietic stem and progenitor cells.

Patta I et al. Nucleic Acids Res 2020; 48 (11):5873-5890 Dynamic regulation of chromatin organizer SATB1 via TCR-induced alternative promoter switch during T-cell development.

Ng AP et al. Nat Commun 2020; 11 (1):3013 An Erg-driven transcriptional program controls B cell lymphopoiesis.

Voloshin T et al. Cancer Immunol Immunother 2020; 69 (7):1191-1204 Tumor-treating fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy.

White JM et al. Mol Pharm 2020; 17 (6):2099-2108 Removal of Fc Glycans from [⁸⁹Zr]Zr-DFO-Anti-CD8 Prevents Peripheral Depletion of CD8⁺ T Cells.

McCarthy CE et al. Front Immunol 2020; 11:1067 In vivo Imaging Technologies to Monitor the Immune System.

Ganugula R et al. Sci Adv 2020; 6 (24):eabb3900 A highly potent lymphatic system-targeting nanoparticle cyclosporine prevents glomerulonephritis in mouse model of lupus.

Israelow B et al. bioRxiv 2020; Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.

Kim EH et al. Elife 2020; 9 Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway.

Lim CS et al. Front Immunol 2020; 11:1186 Resolution of Pulmonary Inflammation Induced by Carbon Nanotubes and Fullerenes in Mice: Role of Macrophage Polarization.

Prinz D et al. Eur J Immunol 2020; 50 (6):880-890 Loss of NKG2D in murine NK cells leads to increased perforin production upon long-term stimulation with IL-2.

Viar K et al. PLoS One 2020; 15 (6):e0235110 Sarm1 knockout protects against early but not late axonal degeneration in experimental allergic encephalomyelitis.

Dunst J et al. J Leukoc Biol 2020; 107 (6):1033-1044 Recognition of synthetic polyanionic ligands underlies "spontaneous" reactivity of Vγ1 γδTCRs.

Zhai W et al. Acta Pharm Sin B 2020; 10 (6):1047-1060 A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8⁺ T cell responses.

John S et al. Sci Rep 2020; 10 (1):11377 Bioluminescence for in vivo detection of cell-type-specific inflammation in a mouse model of uveitis.

Wang S et al. Cell Res 2020; 30 (7):610-622 Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer.

Benitez AA et al. Commun Biol 2020; 3 (1):355 Absence of central tolerance in Aire-deficient mice synergizes with immune-checkpoint inhibition to enhance antitumor responses.

Pessoa Rodrigues C et al. Sci Adv 2020; 6 (21):eaaz4815 Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate.

Burns JC et al. Elife 2020; 9 Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain.

Brito RCF et al. Vaccines (Basel) 2020; 8 (2) Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral Leishmaniasis.

Chen Y et al. Virol Sin 2020; Freeze-Drying Formulations Increased the Adenovirus and Poxvirus Vaccine Storage Times and Antigen Stabilities.

Yamane K et al. Sci Rep 2020; 10 (1):12086 Mitomycin C treatment improves pancreatic islet graft longevity in intraportal islet transplantation by suppressing proinflammatory response.

?ledzi?ska A et al. Immunity 2020; 52 (1):151-166.e6 Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.

Pionnier N et al. J Immunol 2020; 205 (3):731-740 Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor Signaling.

Israelow B et al. SSRN 2020;:3628297 Mouse Model of SARS-CoV-2 Reveals Inflammatory Role of Type I Interferon Signaling.

Van Den Eeckhout B et al. NPJ Vaccines 2020; 5:64 Specific targeting of IL-1β activity to CD8⁺ T cells allows for safe use as a vaccine adjuvant.

Batista SJ et al. Nat Commun 2020; 11 (1):3687 Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection.

Briukhovetska D et al. Front Immunol 2020; 11:1397 C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection.

ElTanbouly MA et al. Science 2020; 367 (6475) VISTA is a checkpoint regulator for na?ve T cell quiescence and peripheral tolerance.

Laczk? D et al. Immunity 2020; A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.

Jandke A et al. Nat Commun 2020; 11 (1):3769 Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments.

Buqu? A et al. Nat Commun 2020; 11 (1):3819 Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.

Im JH et al. Nat Commun 2020; 11 (1):4064 FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy.

Forsyth KS et al. PLoS Pathog 2020; 16 (8):e1008685 Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+?T cells post peptide loading.

Stotesbury C et al. Aging Cell 2020; 19 (7) Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation.

Lechuga-Vieco AV et al. Sci Adv 2020; 6 (31):eaba5345 Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics.

Tada S et al. Transplant Direct 2020; 6 (9):e591 The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation.

Gawriluk TR et al. Front Immunol 2020; 11:1695 Complex Tissue Regeneration in Mammals Is Associated With Reduced Inflammatory Cytokines and an Influx of T Cells.

Bonifacius A et al. Front Immunol 2020; 11:1579 Staphylococcus aureus Alpha-Toxin Limits Type 1 While Fostering Type 3 Immune Responses.

Liang Y et al. J Neuroinflammation 2020; 17 (1):249 IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice.

Wu S et al. Nat Commun 2020; 11 (1):4081 A single dose of an adenovirus-vectored vaccine provides protection against SARS-CoV-2 challenge.

Wang D et al. J Neuroinflammation 2020; 17 (1):257 FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages.

Esaki S et al. Cancer Gene Ther 2020; 27 (7-8):585-598 Oncolytic activity of HF10 in head and neck squamous cell carcinomas.

Sahputra R et al. J Mol Med (Berl) 2020; 98 (9):1301-1317 Investigating the importance of B cells and antibodies during Trichuris muris infection using the IgMi mouse.

Janssen E et al. JCI Insight 2020; 5 (15) DOCK8 is essential for LFA-1-dependent positioning of T follicular helper cells in germinal centers.

Weidner H et al. JCI Insight 2020; 5 (15) Increased FGF-23 levels are linked to ineffective erythropoiesis and impaired bone mineralization in myelodysplastic syndromes.

Shah S et al. Pathogens 2020; 9 (8) MCMV Dissemination from Latently-Infected Allografts Following Transplantation into Pre-Tolerized Recipients.

Cassidy BR et al. J Neuroinflammation 2020; 17 (1):259 Neuroinvasive Listeria monocytogenes infection triggers accumulation of brain CD8⁺ tissue-resident memory T cells in a miR-155-dependent fashion.

Dhayade S et al. Nutrients 2020; 12 (8) Impact of Formate Supplementation on Body Weight and Plasma Amino Acids.

1989; Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex.

CD3 antibody [17A2] (PerCP-Cy5.5)

Référence GTX01458-11-100ug

Contactez votre distributeur local :

Marque : GeneTex

Contactez votre distributeur local :

Host

Clonality

Clone Name

Isotype

Application

Reactivity