CTLA4 antibody [BNI3] (PE-Cy7)
Référence GTX00492-10-100test
Conditionnement : 100test
Marque : Genetex
Host | Mouse |
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Clonality | Monoclonal |
Clone Name | BNI3 |
Isotype | IgG2a |
Application | FACS |
Reactivity | Human |
Package | 100 test |
View product citations for antibody GTX00492-10 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application | Recommended Dilution |
---|---|
FACS | 4 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension |
Not tested in other applications.
Calculated MW
25 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human CD152-IgG heavy chain fusion protein
Purification
Purified by size-exclusion chromatography
Conjugation
Phycoerythrin-Cyanine7 (PE-Cy7)
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
TARGET
Synonyms
ALPS5 , CD , CD152 , CELIAC3 , CTLA4 , GRD4 , GSE , IDDM12 , cytotoxic Tlymphocyte associated protein 4 , cytotoxic T-lymphocyte associated protein 4
Cellular Localization
Cell membrane
Background
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Database
Clone Reference
Zhao Y et al. Biomed Pharmacother 2017; 90:147-152 Enhance the anti-renca carcinoma effect of a DNA vaccine targeting G250 gene by co-expression with cytotoxic T-lymphocyte associated antigen-4(CTLA-4).
REVIEW
Clone Reference
Zhao Y et al. Biomed Pharmacother 2017; 90:147-152 Enhance the anti-renca carcinoma effect of a DNA vaccine targeting G250 gene by co-expression with cytotoxic T-lymphocyte associated antigen-4(CTLA-4).
SDS | |
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PBS.pdf | |
Sodium Azide.pdf |
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Référence
Description
Cond.
Prix HT