- More Files
- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DRD3.
Immunogen
A synthetic peptide corresponding to 18 amino acid at cytoplasmic domain of human DRD3.
Host
Rabbit
Reactivity
Dog, Hamster, Horse, Human, Monkey, Mouse, Pig
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (16-32 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human brain, globus pallidus with DRD3 polyclonal antibody (Cat # PAB26230). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. - Gene Info — DRD3
Entrez GeneID
1814Protein Accession#
P35462Gene Name
DRD3
Gene Alias
D3DR, ETM1, FET1, MGC149204, MGC149205
Gene Description
dopamine receptor D3
Gene Ontology
HyperlinkGene Summary
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq
Other Designations
essential tremor 1
- Interactomes
- Pathways
- Diseases