Eprodisate (disodium) [36589-58-9]
Référence HY-B1141-1ml
Conditionnement : 10mM/1mL
Marque : MedChemExpress
Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
Eprodisate disodium Chemical Structure
CAS No. : 36589-58-9
This product is a controlled substance and not for sale in your territory.
Description |
Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. |
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Essai clinique |
|
||||||||||||
Masse moléculaire |
248.19 |
||||||||||||
Formule |
C3H6Na2O6S2 |
||||||||||||
CAS No. |
36589-58-9 |
||||||||||||
Appearance |
Solid |
||||||||||||
Color |
White to off-white |
||||||||||||
SMILES |
O=S(CCCS(=O)(O[Na])=O)(O[Na])=O |
||||||||||||
Livraison | Room temperature in continental US; may vary elsewhere. |
||||||||||||
Stockage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
||||||||||||
Solvant et solubilité |
In Vitro:
H2O : 50 mg/mL (201.46 mM; Need ultrasonic) DMSO : 7.69 mg/mL (30.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
|
||||||||||||
Pureté et documentation |
Purity: ≥98.0% |
Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
---|
DMSO / H2O | 1 mM | 4.0292 mL | 20.1459 mL | 40.2917 mL | 100.7293 mL |
5 mM | 0.8058 mL | 4.0292 mL | 8.0583 mL | 20.1459 mL | |
10 mM | 0.4029 mL | 2.0146 mL | 4.0292 mL | 10.0729 mL | |
15 mM | 0.2686 mL | 1.3431 mL | 2.6861 mL | 6.7153 mL | |
20 mM | 0.2015 mL | 1.0073 mL | 2.0146 mL | 5.0365 mL | |
25 mM | 0.1612 mL | 0.8058 mL | 1.6117 mL | 4.0292 mL | |
30 mM | 0.1343 mL | 0.6715 mL | 1.3431 mL | 3.3576 mL | |
H2O | 40 mM | 0.1007 mL | 0.5036 mL | 1.0073 mL | 2.5182 mL |
50 mM | 0.0806 mL | 0.4029 mL | 0.8058 mL | 2.0146 mL | |
60 mM | 0.0672 mL | 0.3358 mL | 0.6715 mL | 1.6788 mL | |
80 mM | 0.0504 mL | 0.2518 mL | 0.5036 mL | 1.2591 mL | |
100 mM | 0.0403 mL | 0.2015 mL | 0.4029 mL | 1.0073 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.