HMGA2 Rabbit Polyclonal Antibody
Référence TA308757
Conditionnement : 100ul
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HMGA2 Rabbit Polyclonal Antibody
SKU
TA308757
Rabbit polyclonal antibody to HMGA2 (high mobility group AT-hook 2)
| Product Data | |
| Application | IF, IHC, IP, WB |
|---|---|
| Application | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000 |
| Reactivity | Human (Predicted: Pig) |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926) |
| Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 12 kDa |
| Gene Name | high mobility group AT-hook 2 |
| Database Link | |
| Background | This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
| Synonyms | BABL; HMGI-C; HMGIC; LIPO; STQTL9 |
| Note | Seq homology of immunogen across species: Pig (88%) |
| Reference Data | |
| Protein Families | Druggable Genome |
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