General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.093ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This LACTb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | LACTB |
| Gene ID: | 114294 |
| Uniprot ID: | LACTB_HUMAN |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Expressed predominantly in skeletal muscle. |
| Post Translational Modifications | |
| Function | Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism. |
| Protein Name | Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial |
| Database Links | |
| Cellular Localisation | Mitochondrion |
| Alternative ELISA Names | Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial ELISA kitLACTB ELISA kitMRPL56 ELISA kitUNQ843 ELISA kitPRO1781 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance