Human Pyruvate Kinase (PKLR) activation kit by CRISPRa
Référence GA103574
Conditionnement : 1kit
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Human Pyruvate Kinase (PKLR) activation kit by CRISPRa
SKU
GA103574
PKLR CRISPRa kit - CRISPR gene activation of human pyruvate kinase L/R
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | PKLR |
| Locus ID | 5313 |
| Components | GA103574G1, Pyruvate Kinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103574G2, Pyruvate Kinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103574G3, Pyruvate Kinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000298, NM_181871 |
| UniProt ID | P30613 |
| Synonyms | PK1; PKL; PKR; PKRL; RPK |
| Summary | The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN406455 | PKLR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.