NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A) (Azide free) (HRP)

Référence 039007-HRP-200ul

Conditionnement : 200ul

Marque : US Biological

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039007-HRP Rabbit Anti-NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A) (Azide free) (HRP)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
P78426
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_006159.2
Gene #
NKX6-1
Shipping Temp
Blue Ice
Storage Temp
-20°C

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM].||Applications:|Suitable for use in Western Blot, ELISA||Recommended Dilution:|ELISA: 1:1,000|Western Blot: 1:100-500||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).|Purity: Purified by Protein A affinity chromatography.|Immunogen: NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the C-terminal region of human NKX6-1.|Specificity: Human, mouse||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the C-terminal region of human NKX6-1.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
References
Donelan, W., et al. J. Biol. Chem. 285(16):12181-12189(2010)|Zhu, S., et al. Dig. Dis. Sci. 54(5):996-1002(2009)|Schisler, J.C., et al. Mol. Cell. Biol. 28(10):3465-3476(2008)|Yokoi, N., et al. Diabetes 55(8):2379-2386(2006)|Hori, Y., et al. PLoS Med. 2 (4), E103 (2005) :