NMDA 1 Receptor (NMDA R1, N-methyl-D-aspartate) (Biotin)
Référence N2904-35-Biotin-100ul
Conditionnement : 100ul
Marque : US Biological
N2904-35-Biotin NMDA 1 Receptor (NMDA R1, N-methyl-D-aspartate) (Biotin)
Clone Type
PolyclonalHost
mouseSwiss Prot
Q05586Isotype
IgG2aGrade
Affinity PurifiedApplications
E IC IHC RIACrossreactivity
Hu Mk Rt XeAccession #
NM_000832.5Shipping Temp
Blue IceStorage Temp
-20°CThe ion channels activated by glutamate are divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by kainate and a-amino-3-hydroxy-5-methyl- 4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). NMDA receptors are among the most studied receptors in neuroscience. They are involved in neuronal cell development and plasticity, a cellular correlate for learning. NMDA receptors are implicated in several disorders of the central nervous system including epilepsy and ischemic neuronal cell death. NMDA receptors appear to be a target for ethanol at physiological concentrations which may play a significant role in alcoholism.||Applications:|Suitable for use in Immunohistochemistry, Immunocytochemistry, Light and Electron Microscopy, ELISA and RIA. Other applications have not been tested.||Recommended Dilution:|Immunohistochemistry (Paraffin): Use standard deparaffinization techniques on tissue specimens. Pretreat tissues using a citrate buffer, pH 6.0 and high heat epitope retrieval techniques. Do not allow tissues to dry out during the staining procedure.|Optimal dilution determined by the researcher.||Immunohistochemistry Control:|rat brain and spinal cord tissue||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.