NOD2 (Internal) blocking peptide
Référence GTX89233-PEP
Conditionnement : 100ug
Marque : GeneTex
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Species | Human |
|---|---|
| Package | 100 μg |
Datasheet File View product citations for antibody GTX89233-PEP on CiteAb
APPLICATION
Product Note
The peptide was used in the production of GTX89233.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
KFRFTDRERHCSPTD
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Nucleotide Binding Oligomerization Domain Containing 2 , Acug , Blau , Blaus , Card15 , Cd , Clr16.3 , Ibd1 , Nlrc2 , Nod2B , Psoras1 , Yaos , Nod2
Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]