p53BP1 (Ser25 + Ser29) Antibody
Référence bs-3020R-20ul
Conditionnement : 20ul
Marque : Bioss
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p53BP1 (Ser25 + Ser29) Antibody
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti phospho-p53BP1(Ser25\/29) Polyclonal Antibody, Unconjugated (bs-3020R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti phospho-p53BP1(Ser25\/29) Polyclonal Antibody, Unconjugated (bs-3020R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-3020R |
| Product Name | p53BP1 (Ser25 + Ser29) Antibody |
| Applications | ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
| Specificity | This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat. |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Dog, Cow, Pig, Horse, Rabbit |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29 |
| Modification Site | Ser25 + Ser29 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 7158 |
| Swiss Prot | Q12888 |
| Subcellular location | Nucleus |
| Synonyms | p202; 53BP1; Tumor suppressor p53-binding protein 1; p53-binding protein 1; p53BP1; TP53BP1 |
| Background | Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. |
| Application Dilution | |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
| ICC | 1:100-500 |