Recombinant Mouse M-CSF
Référence RP0462M-100
Conditionnement : 100ug
Marque : Kingfisher Biotech
Macrophage colony-stimulating factor (M-CSF), also known as CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF enhances expression of differentiation antigens and stimulates chemotactic, phagocytic and the killing activities of monocytes. M-CSF also stimulates production of several cytokines, including GM- CSF, G-CSF and IL-6 by priming monocytes. It also stimulates production and secretion of IL-8 and reactive nitrogen intermediates. In addition to the stimulation of hematopoiesis, M-CSF also stimulates differentiation and proliferation of osteoclast progenitor cells and cytotrophoblasts.
Alternate Names - CSF1, CSF-1, MCSF, M-CSF, colony stimulating factor 1
Homology Across Species
Mus musculus (house mouse) M-CSF – 100%
Mus caroli (Ryukyu mouse) M-CSF – 99%
Mus pahari (shrew mouse) M-CSF – 98%
