Ruxilitinib

Ruxilitinib is a small molecule which can act as a JAK inhibitor. It is provided as a white powder. It is a Janus-associated kinases (JAK) inhibitor, which specifically inhibits JAK1 and JAK3. JAKs are known to active the signaling of certain growth factor receptors and cytokines.

This product acts on the following target types: Kinase.
This product acts on the following biochemical pathways: Cytokine, Proliferation, JAK/STAT.
This product may be of interest in the following research areas and diseases: Inflammation, Cancer.
This product may act as a Coronavirus inhibitor: Inhibits MARK2/3, which interact with SARS-CoV-2 Orf9b.

Please note that our chemical products are for scientific research use only and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.

Target	Ruxilitinib
Form	Solid
Purity	> 98% (HPLC). Conforms to structure by NMR.
Reconstitution	Soluble in DMSO (up to 28 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
Storage	Store desiccated at -20 °C for up to 2 years. Solutions can be stored at -20 °C for up to 3 months.
Molecular Weight	306.4 g/mol
Molecular Formula	C17H18N6
Buffer	Not applicable.
CAS Number	941678-49-5
SMILES	C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
Availability	Shipped within 5-10 working days.
Note	This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Research Articles on Ruxilitinib