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- Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TACR1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TACR1.
Host
Rabbit
Reactivity
Human, Rat
Specificity
This is specific to human NK-1. This product may be used for Western blotting where a band is seen at ~53 KDa representing human NK-1. The actual molecular weight may vary depending upon the tissue used.
Form
Liquid
Conjugation
DyLight 550
Purification
Immunogen affinity purification
Recommend Usage
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium borate (0.05% sodium azide).
Storage Instruction
Store at 4°C in the dark.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Immunohistochemistry
Flow Cytometry
- Gene Info — TACR1
Entrez GeneID
6869Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
- Interactomes
- Pathways
- Diseases
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
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