UBE2M Polyclonal Antibody, PE-Cy3 Conjugated
Référence bs-8382R-PE-Cy3
Conditionnement : 100ul
Marque : Bioss
UBE2M Polyclonal Antibody, PE-Cy3 Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-8382R-PE-Cy3 |
Product Name | UBE2M Polyclonal Antibody, PE-Cy3 Conjugated |
Applications | WB |
Reactivity | Xenopus laevis |
Predicted Reactivity | Human, Mouse, Rat, Cow, Horse |
Specifications | |
Conjugation | PE-Cy3 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human UBE2M |
Immunogen Range | 1-100/183 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 9040 |
Subcellular location | Cytoplasm, Nucleus, Secreted, Extracellular matrix |
Synonyms | hUbc12; NEDD8 carrier protein; NEDD8 conjugating enzyme Ubc12; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC-RS2; UBC12; UBC12_HUMAN; ube2m; ubiquitin carrier protein M; Ubiquitin conjugating enzyme E2 M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-protein ligase M; yeast UBC12 homolog. |
Background | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. |
Application Dilution | |
WB | 1:300-5000 |