VWF antibody
Référence GTX74137-50ul
Conditionnement : 50ul
Marque : Genetex
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Host | Sheep |
|---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | ICC/IF, IHC-Fr, FACS, ELISA, Immunodiffusion |
Reactivity | Human, Rat |
| Package | 50 μl |
Datasheet File View product citations for antibody GTX74137 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| ICC/IF | Assay dependent |
| IHC-Fr | Assay dependent |
| FACS | Assay dependent |
| ELISA | Assay dependent |
| Immunodiffusion | Neat |
Not tested in other applications.
Calculated MW
309 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
Glycine buffered saline, 0.01% Benzamidine, 0.1%EACA, 1mM EDTA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified human von Willebrand factor prepared from citrated human plasma
Purification
Purified by ion exchange chromatography
Conjugation
Unconjugated
RRID
AB_377840
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
von Willebrand factor , F8VWF , VWD
Cellular Localization
Secreted
Background
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
Database
Application Reference
Portillo JC et al. Cells 2024; 13 (5) Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and M?ller Cells: Relevance to Diabetic Retinopathy.
Vos S et al. Invest Ophthalmol Vis Sci 2023; 64 (7) : 17 CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
Yin T et al. Bioact Mater 2022; 10 : 378-396 Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Application : ICC/IF
Perriard G et al. J Neuroinflammation 2015; 12 : 119 Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Application : ICC/IF
Reactivity : Human
REVIEW
Application Reference
Portillo JC et al. Cells 2024; 13 (5) Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and M?ller Cells: Relevance to Diabetic Retinopathy.
Vos S et al. Invest Ophthalmol Vis Sci 2023; 64 (7):17 CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
Yin T et al. Bioact Mater 2022; 10:378-396 Two-stage degradation and novel functional endothelium characteristics of a 3-D printed bioresorbable scaffold.
Application : ICC/IF
Perriard G et al. J Neuroinflammation 2015; 12:119 Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Application : ICC/IF
Reactivity : Human
| SDS | |
|---|---|
| Sodium Azide.pdf | |