AF38469 [1531634-31-7]
Référence HY-12802-5mg
Conditionnement : 5mg
Marque : MedChemExpress
AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM.
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AF38469 Chemical Structure
CAS No. : 1531634-31-7
This product is a controlled substance and not for sale in your territory.
Based on 9 publication(s) in Google Scholar
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AF38469 purchased from MedChemExpress. Usage Cited in: Am J Pathol. 2020 Sep;190(9):1931-1942. [Abstract]
- Western blot detection of phosphorylation of FAK (Tyr925), FAK (Tyr397) and FAK (Tyr576/577) in the treatment with AF38469. The phosphorylation of residue Tyr925 of FAK is decreased in sortilin-inhibited compared to NT control.
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AF38469 purchased from MedChemExpress. Usage Cited in: Breast Cancer Res. 2018 Nov 20;20(1):137. [Abstract]
- Immunohistochemical analyses of the GRN A- and AF38469-treated groups of MDA-MB 231 luc xenografts with skin is performed using Ki67 and haematoxylin staining.