Anti-GABA Transporter 2 (GAT2) (Rabbit) Antibody
Référence 612-401-D57
Conditionnement : 100ul
Marque : Rockland Immunochemicals
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Téléphone : +1 850 650 7790
Specifications for GABA Transporter 2 (GAT2) Antibody
Product Details
Anti-GABA Transporter 2 (GAT2) (RABBIT) Antibody - 612-401-D57
Sodium- and chloride-dependent GABA transporter 2, Solute carrier family 6 member 13, Slc6a13, Gabt2, Gat-2
Rabbit
Polyclonal
IgG
Target Details
Slc6a13 - View All Slc6a13 Products
Rat
Conjugated Peptide
Anti-GABA Transporter 2 Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.
Anti-GAT2 antibody is directed against rat GAT2 protein. GABA Transporter 2 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity is expected from the following species based on 100% sequence homology: mouse.
P31646 - UniProtKB
NP_598307.1 - NCBI Protein
Application Details
IHC, WB
Anti-GAT2 (Rabbit) Antibody is tested for use in WB and IHC. Specific conditions for reactivity should be optimized by the end user. GAT2 antibody is specific for the approximately 82 kDa in size GABA Transporter 2 protein.
Formulation
0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
0.1 mg/ml Bovine Serum Albumin (BSA) - IgG and Protease free, 50% (v/v) Glycerol
Shipping & Handling
Dry Ice
Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
Expiration date is one (1) year from date of receipt.
Background
GAT2 Antibody detects rat GAT2 protein. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex. Anti-GAT2 Antibody is ideal for investigators involved in Neuroscience.
Related Protocols
Adherent Cell Lysis Protocol
Fluorescent Western Blotting Protocol
Heat-induced Antigen Retrieval Protocol
Histone Immunoblotting Protocol
Immunohistochemistry (IHC) Protocol
In-Cell Western (ICW) Protocol
IP-WB with TrueBlot® Protocol
Multi-Lysate Western Blotting Protocol
Nuclear & Cytoplasmic Extract Protocol
Protease-induced Antigen Retrieval Protocol
Staining Paraffin Sections by PAP Procedure
Suspension Cultured Cell Lysis Protocol
Western Blotting (WB) Protocol
Certificate of Analysis Lookup
Disclaimer
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.
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