Anti-PDE4D7 antibody {Biotin}

Clonality:	Polyclonal
Conjugation:	Biotin
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.2 µg/µl
Dilution Range:	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:150
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Pde4d
Gene ID:	238871
Uniprot ID:	PDE4D_MOUSE
Specificity:	Does not crossDoes not cross react with other PDE family members including PDE4A, PDE4B or PDE4C.
Immunogen:	Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant.

Tissue Specificity	Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis.
Post Translational Modifications	Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation.
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Protein Name	Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4d Dpde3
Database Links	Reactome: R-MMU-180024 Reactome: -MMU-418555
Cellular Localisation	Cytoplasm Membrane Cytoskeleton Microtubule Organizing Center Centrosome Apical Cell Membrane Colocalized With Shank2 To The Apical Membrane Of Colonic Crypt Cells Found In The Soluble Fraction Associated With Membranes And Associated With The Cytoskeleton And The Centrosome
Alternative Antibody Names	Anti-Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4d antibody Anti-Dpde3 antibody Anti-Pde4d antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance