Baricitinib-d3 [1564242-30-3]
Référence HY-15315S1-1mg
Conditionnement : 1mg
Marque : MedChemExpress
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
Baricitinib-d3 is the deuterium labeled Baricitinib. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
Baricitinib-d3 Chemical Structure
CAS No. : 1564242-30-3
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Baricitinib-d3:
- Baricitinib In-stock
Voir tous les produits spécifiques à Isoform JAK:
| Description |
Baricitinib-d3 is the deuterium labeled Baricitinib. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
|||||||||
| Masse moléculaire |
374.44 |
|||||||||
| Formule |
C16H14D3N7O2S |
|||||||||
| CAS No. |
1564242-30-3 |
|||||||||
| Unlabeled CAS |
1187594-09-7 |
|||||||||
| Appearance |
Solid |
|||||||||
| Color |
White to off-white |
|||||||||
| SMILES |
N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(S(=O)(CC([2H])([2H])[2H])=O)C1 |
|||||||||
| Livraison | Room temperature in continental US; may vary elsewhere. |
|||||||||
| Stockage |
|
|||||||||
| Pureté et documentation |
Purity: ≥99.0%
SDS (252 KB)
COA (259 KB) HNMR (128 KB) RP-HPLC (177 KB) LCMS (88 KB) Instruction de manipulation (2659 KB) |
|||||||||
| Références |
|
Baricitinib-d3 Related Classifications
- Inflammation/Immunology
- Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
- JAK
Calculateur de molarité
Calculateur de dilution
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
-
Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Baricitinib-d31564242-30-3LY3009104-d3INCB028050-d3JAKJanus kinaseInhibitorinhibitorinhibit