BCR/ABL (ES) Gene Fusion Detection BioGenomics™ FISH Kit

Sample Type: |Bone marrow||Intended Use:|FISH||Probe Name:|GLP BCR/GLP ABL (22q11/9q34)||Fluorophore:|Orange/Green||Clinical Significance:|1. Adjuvant diagnosis of Chronic Myeloid Leukemia, BCR/ABL positive fusion is a Chronic Myeloid Leukemia (CML) characteristic gene change.|2. BCR/ABL(ES) probe can differentiate the primary and secondary BCR rupture points, identify acute CML mutations and Philadelphia chromosome-positive acute leukemia;|3. Guide the clinical targeted drug Imatinib (Gleevec, Glivec) treatment;|4. Determine the prognosis suggests that ASS gene deletion is associated with poor prognosis in patients with CML deletion.||Storage and Stability:|Store powder at 4°C liquid at -20°C. Store other components at 4°C. Stable for 6 months For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.