BIX01294 (hydrochloride hydrate) [1808255-64-2]
Référence T35567-100mg
Conditionnement : 100mg
Marque : TargetMol
BIX01294 (hydrochloride hydrate)
Contact us for more batch information
BIX01294 (hydrochloride hydrate)
Catalog No. T35567Cas No. 1808255-64-2
The methylation of lysine residues on histones plays a central role in determining euchromatin structure and gene expression. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294 (hydrochloride hydrate) is a selective inhibitor of G9a HMTase (IC50 = 1.7 μM). It less effectively inhibits the HMTase G9a-like protein (GLP; IC50 = 38 μM) and has no effect on other known HMTases. BIX01294 has been used in combination with the calcium channel activator BayK8644 to facilitate the generation of induced pluripotent stem cells from somatic cells in vitro.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. Pack Size | |
---|---|
1 mg | |
5 mg | |
10 mg | |
50 mg |