CYP27A1 Human shRNA Plasmid Kit (Locus ID 1593)

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CYP27A1 Human shRNA Plasmid Kit (Locus ID 1593)

Specifications
Product Data
Locus ID 1593
Synonyms CP27; CTX; CYP27
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components CYP27A1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1593). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_000784, NM_000784.1, NM_000784.2, NM_000784.3, BC017044, BC040430, BC051851, NM_000784.4
UniProt ID Q02318
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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