Orb180837-250mg | DAPAGLIFLOZIN Clinisciences

DAPAGLIFLOZIN

Catalog Number	orb180837
Category	Small Molecules
Description	Dapagliflozin, also known as BMS-512148, is a drug used to treat type 2 diabetes approved in 2012 by FDA. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Blocking this transporter mechanism causes blood glucose to be eliminated through the urine. In clinical trials, dapagliflozin lowered HbA1c by 0.6 versus placebo percentage points when added to metformin.
CAS Number	[461432-26-8]
MW	408.87
SMILES	O[C@H]1[C@H](C2=CC=C(Cl)C(CC3=CC=C(OCC)C=C3)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O
Formula	C₂₁H₂₅ClO₆
Note	For research use only
Expiration Date	12 months from date of receipt.

Chemical structure of DAPAGLIFLOZIN