Dextran sulfate sodium salt
Référence M9443-50g
Conditionnement : 50g
Marque : AbMole Bioscience
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DSS
Quality Control & Documentation
Biological Activity
Dextran sulfate sodium salt is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. Dextran Sulfate Sodium (DSS) can be used to study Colitis (Inflammatory Bowel disease) as well as an antiviral as agent.Oral administration of dextran sulfate induces colonic inflammation in a mouse model of inflammatory bowel disease (IBD). Acute, chronic, and relapsing models of IBD can be induced by varying the concentration and administration frequency of dextran sulfate.
Product Citations
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Biomed Pharmacother. 2024 Jun 26.
Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation
Dextran sulfate sodium salt purchased from AbMole -
Biomed Pharmacother. 2023 Sep;165:115273.
Discovery of a novel small molecule with efficacy in protecting against inflammation in vitro and in vivo by enhancing macrophages activation
Dextran sulfate sodium salt purchased from AbMole
Chemical Information
| Formula | (C6H7Na3O14S3)n |
| CAS Number | 9011-18-1 |
| Solubility (25°C) | Water 100 mg/mL |
| Storage | 2-8°C, sealed |
References
[1] Baba M, et al. Proc Natl Acad Sci U S A. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.