Dimethyl sulfoxide [67-68-5]

Référence T0341-100mL

Conditionnement : 100mL

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Dimethyl sulfoxide

Dimethyl sulfoxide
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Dimethyl sulfoxide

Catalog No. T0341Cas No. 67-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
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Pack Size
100 mL
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Product Introduction

Bioactivity
Description
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
In vitro
METHODS: Human colorectal cancer cells HCT-116 and SW-480 were treated with Dimethyl sulfoxide (0.1%-1.5%) for 24 h, and cell viability was measured by MTT.
RESULTS: Dimethyl sulfoxide showed a dose-dependent effect on cell proliferation. Cells treated with 1.5% Dimethyl sulfoxide showed about 10% reduction in cell growth. [1]
In vivo
METHODS: To detect toxicity, Dimethyl sulfoxide (10%-100%) was administered to Swiss mice by single intraperitoneal injection for five days.
RESULTS: The LD50 increased with decreasing concentration and the LD50 values for 10%, 25%, 50%, 75%, and 100% Dimethyl sulfoxide were >10.1, 15.4, 13.3, 11.9, and 10.9 g/kg, respectively. [2]
AliasMethyl Sulfoxide, DMSO
Chemical Properties
Molecular Weight78.13
FormulaC2H6OS
Cas No.67-68-5
Storage & Solubility Information
Storagestore at RT | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

solventbacteriostaticBacterialInhibitorinhibitanti-freezinganti-inflammatoryaproticDimethyl sulfoxide
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