EPM2A (Lafora Disease Epilepsy Progressive Myoclonus Type 2A, EPM2, MELF)

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.||Applications: |Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry. Other applications not tested.||Recommended Dilution: |Immunofluorescence: 1:50-1:100|Western Blot: 1:500-1:2000|Immunohistochemistry: 1:50-1:200|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.