GBA Human shRNA Plasmid Kit (Locus ID 2629)
Référence TR312830
Conditionnement : 1kit
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GBA Human shRNA Plasmid Kit (Locus ID 2629)
SKU
TR312830
GBA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
In Stock*
| Product Data | |
| Locus ID | 2629 |
|---|---|
| Synonyms | GBA1; GCB; GLUC |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Format | Retroviral plasmids |
| Components | GBA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2629). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000157, NM_001005741, NM_001005742, NM_001005749, NM_001005750, NM_001171811, NM_001171812, NM_001005741.1, NM_001005741.2, NM_001005742.1, NM_001005742.2, NM_000157.1, NM_000157.2, NM_000157.3, NM_001171811.1, NM_001171812.1, NM_001005749.1, NM_001005750.1, BC003356, BC003356.1, NM_001005741.3, NM_001005742.3, NM_001171812.2, NM_000157.4 |
| UniProt ID | P04062 |
| Summary | This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.