HepG2 cells
Référence C0015002
Conditionnement : OneFrozenvial
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Disease:
Hepatocellular carcinoma Established from the tumor tissue of a 15-year-old Argentine boy Homo sapiens Liver Epithelial Adherent human hyperdiploid karyotype Male, 15 yrs of age AddexBio-formulated RPMI-1640 Medium(C0004-01) + 10% FBS 1:2 to 1:4 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37°C Complete culture medium supplemented with 5% (v/v) DMSO Bacteria: Negative Yeast: Negative Mycoplasma: Negative HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Hep3B cells HepG2 cells Origin:
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Cytogenic data:
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Freezing Medium:
Biosafety Level:
I Sterility:
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Protein Expression:
Express insulin, insulin-like growth factor II (IGF II), 3-hydroxy-3-methylglutaryl-CoA reductase and hepatic triglyceride lipase activities; decreased expression of apoA-I mRNA and increased expression of catalase mRNA in response to gramoxone DNA Profile (STR):
Amelogenin: X,Y CSF1PO: 10,11 D13S317: 9,13 D16S539: 12,13 D5S818: 11,13 D7S820: 10 THO1: 9 TPOX: 8,9 vWA: 17 D3S1358: 15,16 D21S11: 29,31 D18S51: 13,14 Penta E: 15,20 Penta D: 9,13 D8S1179: 15,16/17 FGA: 22,25 Related cells by Organ:
References for HepG2 cells:
1. Patlolla, A. K., Barnes, C., Hackett, D., and Tchounwou, P. B. Potassium dichromate induced cytotoxicity, genotoxicity and oxidative stress in human liver carcinoma (HepG2) cells. Int J Environ Res Public Health, 6: 643-653, 2009.
2. Souza, V., Escobar Mdel, C., Bucio, L., Hernandez, E., Gomez-Quiroz, L. E., and Gutierrez Ruiz, M. C. NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. Toxicol Lett, 187: 180-186, 2009.
3. Liu, Z. H. and Zeng, S. Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes. Toxicol Lett, 187: 131-136, 2009.
4. Zhang, X., Cao, J., Jiang, L., Geng, C., and Zhong, L. Protective effect of hydroxytyrosol against acrylamide-induced cytotoxicity and DNA damage in HepG2 cells. Mutat Res, 664: 64-68, 2009.
5. Verma, P., Verma, V., Ray, P., and Ray, A. R. Agar-gelatin hybrid sponge-induced three-dimensional in vitro 'liver-like' HepG2 spheroids for the evaluation of drug cytotoxicity. J Tissue Eng Regen Med, 3: 368-376, 2009.
6. Barcelos, G. R., Angeli, J. P., Serpeloni, J. M., Rocha, B. A., Mantovani, M. S., and Antunes, L. M. Effect of annatto on micronuclei induction by direct and indirect mutagens in HepG2 cells. Environ Mol Mutagen, 50: 808-814, 2009.