Human IL-1 beta ELISpot Pair, 10 x 96-well
Référence EA101818
Conditionnement : 10x96wells
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Human IL-1 beta ELISpot Pair, 10 x 96-well
| Product Data | |
| ACCN | NM_000576 |
|---|---|
| Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
| Assay Type | Sandwich |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008] |
| Components | ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples. |
| Cross Reactivity | No cross reactivity with other human cytokines |
| Format | 10 x 96-well |
| Gene Symbol | IL1B |
| Locus ID | 3553 |
| Signal | Colorimetric |
| Species | Human |
| Specificity | Recognizes natural (pro and mature) human IL-1b |
| Target Symbol | IL1B |
| New | No |
| Description | Human IL-1 beta ELISpot Pair, 10 x 96-well |