Human IL-4 ELISpot Pair, 10 x 96-well
Référence EA101811
Conditionnement : 10x96wells
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Human IL-4 ELISpot Pair, 10 x 96-well
| Product Data | |
| ACCN | NM_000589 |
|---|---|
| Assay Type | Enzyme-Linked ImmunoSpot (ELISpot) |
| Assay Type | Sandwich |
| Background | The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Components | ELISpot matched antibody pairs are extensively validated and include pre-titrated capture antibody and biotinylated detection antibody. Antibodies are supplied in quantities sufficient for 10 x 96 samples. |
| Cross Reactivity | No cross reactivity with other human cytokines |
| Format | 10 x 96-well |
| Gene Symbol | IL4 |
| Locus ID | 3565 |
| Signal | Colorimetric |
| Species | Human |
| Specificity | Recognizes natural human IL-4 |
| Target Symbol | IL4 |
| New | No |
| Description | Human IL-4 ELISpot Pair, 10 x 96-well |