Influenza Virus NS1A Binding Protein (IVNS1ABP) (NM_006469) Human 3' UTR Clone
CAT#: SC215833
3' UTR clone of influenza virus NS1A binding protein (IVNS1ABP) for miRNA target validation
Product Images
Specifications
| Product Data | |
| Vector | pMirTarget |
| Species | Human |
| Transfection Reporter | RFP |
| Assay Reporter | Luciferase |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Symbol | IVNS1ABP |
| Synonyms | ARA3; FLARA3; HSPC068; IMD70; KLHL39; ND1; NS-1; NS1-BP; NS1BP |
| ACCN | NM_006469 |
| Insert Size | 1677 bp |
| Sequence Data | >SC215833 3’UTR clone of NM_006469 The sequence shown below is from the reference sequence of NM_006469. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCCCTATACAAAGATTTTCCAGTTTTAACAAATTTAAGACCCTCTCAAACTAACAGGCTTAGTGATG TAATTATGGTTAGTAGAGGTACACTTGTGAATAAAGAGGGTGGGTGGGTATAGATGTTGCTAACAGCAA CACAAAGCTTTTGCATATTGCATACTATTAAACATGCTGTACATACTTTTTGGGTTTATTTGGAAAGGA ATGCAAAGATGAAGGTCTGTTTTGTGTACTTTTAAGACTTTGGTTATTTTACTTTTTGGAAAAGAATAA ACCAAGAATTGATTGGGCACATCATTTCAAGAAGTCCCCTCTCCTCCACATTTGTTTTGCCAATTTGCA CATTAAATGACTCTTCCCTCAAATGTGTACTATGGGGTAAAAGGGGTAGGGTTTAAAGATGTAGACAGT TGGGTTTTTTAAGGGCCCTTTTTCAATAACTGGAACACTCTATAACAAAGGATACTTATTTAAATAGAT GACATTGACTATTTTTGTTTTTATTAAAAGGAAGCTTACATGCCTACCAATATTTAATCTTTTATGATT GCCTTTTTATAACTTTTTATATTCTCAGCAGAGTGCTTTACCAATTGAAGTAAAATGTGGCAGGCTGGA GTTATTGAAGCAGAGTGGCAGTCTTCAGTTTGCAGAGTAGGGGTCTGTCTTTTAAACTCTGAGTGCAAA CTTCAGAGTTCTTGCCTTGGCTGCAGTTTTTTTCCTTCAAGAATGCAGTACTAACATTTATTTGAGTGG AGTTACTGAACAGTAACATAGCTGTGATTTTTGGTATTTGAAACACTGGTTTTAAATATTTTGACTTGT TGAGGGTATGTTTTATATAGCAAGACATTATATAGCAGTAAAAAATGGTGTTTTATCTTCTATATAATT CCTGTTTTTATTATTAACAAAACAGTCCTAAATAGCAGCCCTCAATTGTGAAAAAATTTACTTTAAACT ACATTAGGTTGTGAATGCAGGTTTTATCAGAACTATGTTTTTGTTCAGTTTATCTGTTCATATGGATAA ATATTGGTTGGGATGACTTGGTGTCTAATGTGTAGTGCTACACACCTAACTTATGGGGCCAAAATAGCA TGTCCTAATGCTTGCTGCTGATTTAAACACATTAAAGGTACTTTGCAGGAAATCCTTGCACCATGGGAT TAATATCCAATTGCTGCTTGTACACTCATTCATTACTAAAAGTTTTGAGAAATTTTTTTTTCCAGTAAT GAGCTTAAGAAATTTGTGGAAAATAACTCACCTGGCATCTTACATCTGAAATAAGGAATGATATAAGGT TTTTTTTTCTCACAGAAGATGAAGCACACAGGAACCTAATGGGCCAACTGGGATGAGGTGACTATTCTG AGATGACTATTCAGTGGCTAACTTGGGTTAGGAAGAAAATAATTAGGTATTTTCTCCAAATGTTCACTG GTACTCTGCCACTTTATTTCTCTCATCTGTTACACAAAGAACCACCAGGAAAGCAAATCAGTTTGGTTG GTAACTCTGTAATTCCTAACTATCACTGGTTTGGTTCTGGACTAAAACTACATTGACAGATTGAATTTG CCTAATATGATGACTGTTTTTAATATGGATCTGTATGTGTTCTATTCAGCACAAGGAAATAAAATTTTA GTTGAGGATTCAGCACTAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
| Restriction Sites | SgfI-MluI |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
| Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
| Reference Data | |
| RefSeq | NM_006469.5 |
| Summary | Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity). Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription (PubMed:16582008). In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors (PubMed:25619834). Inhibits pre-mRNA splicing (in vitro) (PubMed:9696811).[UniProtKB/Swiss-Prot Function] |
| Locus ID | 10625 |
| MW | 64.6 |
Documents
| Product Manuals |
| FAQs |
|
| SDS |