Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.
 
> Interleukin-17; human IL-17 (IL-17A)

Interleukin-17; human IL-17 (IL-17A)

Imprimer Imprimer
Identifiez-vous

Référence RC212-28-5ug

Conditionnement : 5ug

Marque : Bio Basic

Demander plus d'informations

Contactez votre distributeur local :


Téléphone : +1 850 650 7790

IL-17, Interleukin-17 IL-17A, human
Storage: (-15 to -20)C
Product Description: IL-17, Interleukin-17 IL-17A, human: Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. cDNA clones encoding IL-17 have been isolated from activated rat, mouse and human T cells. Human IL-17 cDNA encodes a 155 amino acid (aa) residue precursor protein with a 19 amino acid residue signal peptide that is cleaved to yield the 136 aa residue mature IL-17 containing one potential N-linked glycosylation site. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. At the amino acid level, human IL-17 shows 72% and 63% sequence identity with herpesvirus and rat IL-17, respectively. An IL-17 specific mouse cell surface receptor (IL-17 R) has recently been cloned. While the expression of IL-17 mRNA is restricted to activated T cells, the expression of mIL-17 R mRNA has been detected in virtually all cells and tissues tested. IL-17 exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-κB and costimulation of T cell proliferation., Accession number: NM_002190, UnitProt ID: Q16552
Total Product Size:
RC212-28 (5ug)
RC212-28 (25ug)
RC212-28 (1mg)
Number of Containers: 1
Refrigeration Requirements: Freezer
Shipping Conditions: ICE
UNSPSC Code: 41116127
UNSPSC Category: Other Cytokines and Chemokines
Documents

Vous serez peut-être également intéressé par les produits suivants :



Référence
Description
Cond.
Prix HT
MBS691913-0,01mg
Human TNF-alpha
 0.01mg