LDN-192960 2HCl [184582-62-5]
Référence AOB1696-100
Conditionnement : 100mg
Marque : AOBIOUS
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Data sheet
| Molecular Formula | C18H22Cl2N2O2S |
| Molecular Weight | 401.35 |
| CAS Numbers | 184582-62-5 (free base) |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | LDN-192960 HCl; LDN-192960 hydrochloride; LDN 192960; LDN192960; LDN-192960; |
| IUPAC/Chemical Name | 3-(2,7-Dimethoxy-acridin-9-ylsulfanyl)-propylamine dihydrochloride |
| InChl Key | FNHCUCJBABESJB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H20N2O2S.2ClH/c1-21-12-4-6-16-14(10-12)18(23-9-3-8-19)15-11-13(22-2)5-7-17(15)20-16;;/h4-7,10-11H,3,8-9,19H2,1-2H3;2*1H |
| SMILES Code | NCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31.05Cl.05Cl |
| References | 1) Cuny GD, et al. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3491-4. 2) Katrin Kestav, et al. Structure, Roles and Inhibitors of a Mitotic Protein Kinase Haspin. Curr Med Chem. 2017;24(21):2276-2293. |
More info
Potent and selective haspin inhibitor