Maleic Acid [110-16-7]
Référence HY-Y0367-500mg
Conditionnement : 500mg
Marque : MedChemExpress
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.
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Maleic Acid Chemical Structure
CAS No. : 110-16-7
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
Other Forms of Maleic Acid:
- Maleic Acid-d2 In-stock
Description |
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. |
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IC50 & Target |
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In Vitro |
The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Essai clinique |
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Masse moléculaire |
116.07 |
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Formule |
C4H4O4 |
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CAS No. |
110-16-7 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C(O)/C=C\C(O)=O |
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Structure Classification |
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Initial Source |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
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Solvant et solubilité |
In Vitro:
H2O : 100 mg/mL (861.55 mM; Need ultrasonic) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
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Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Pureté et documentation | |||||||||||||
Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O | 1 mM | 8.6155 mL | 43.0775 mL | 86.1549 mL | 215.3873 mL |
5 mM | 1.7231 mL | 8.6155 mL | 17.2310 mL | 43.0775 mL | |
10 mM | 0.8615 mL | 4.3077 mL | 8.6155 mL | 21.5387 mL | |
15 mM | 0.5744 mL | 2.8718 mL | 5.7437 mL | 14.3592 mL | |
20 mM | 0.4308 mL | 2.1539 mL | 4.3077 mL | 10.7694 mL | |
25 mM | 0.3446 mL | 1.7231 mL | 3.4462 mL | 8.6155 mL | |
30 mM | 0.2872 mL | 1.4359 mL | 2.8718 mL | 7.1796 mL | |
40 mM | 0.2154 mL | 1.0769 mL | 2.1539 mL | 5.3847 mL | |
50 mM | 0.1723 mL | 0.8615 mL | 1.7231 mL | 4.3077 mL | |
60 mM | 0.1436 mL | 0.7180 mL | 1.4359 mL | 3.5898 mL | |
80 mM | 0.1077 mL | 0.5385 mL | 1.0769 mL | 2.6923 mL | |
100 mM | 0.0862 mL | 0.4308 mL | 0.8615 mL | 2.1539 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Maleic Acid Related Classifications
- Metabolic Enzyme/Protease Anti-infection
- Endogenous Metabolite Bacterial