MNK1 (MKNK1) (NM_003684) Human Recombinant Protein
Référence TP301149
Conditionnement : 20ug
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MNK1 (MKNK1) (NM_003684) Human Recombinant Protein
SKU
TP301149
Recombinant protein of human MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 1, 20 µg
- MVPro
Full-length human proteins expressed in HEK293T cells
In Stock*
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence | Protein Sequence >RC201149 protein sequence Red=Cloning site Green=Tags(s) MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQ NGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQK HFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHR DLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDK RCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDL ISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 51.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_003675 |
| Locus ID | 8569 |
| UniProt ID | Q9BUB5 |
| Cytogenetics | 1p33 |
| RefSeq Size | 2827 |
| RefSeq ORF | 1395 |
| Synonyms | MNK1 |
| Summary | This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012] |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Insulin signaling pathway, MAPK signaling pathway |
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Recombinant Protein Resources |
| SKU | Description | Size | ||
|---|---|---|---|---|
| PH301149 | MKNK1 MS Standard C13 and N15-labeled recombinant protein (NP_003675) | 10 ug | | |
| LC404698 | MKNK1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC418502 | MKNK1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LC427613 | MKNK1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug | | |
| LY404698 | Transient overexpression lysate of MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 2 | 100 ug | | |
| LY418502 | Transient overexpression lysate of MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 1 | 100 ug | | |
| LY427613 | Transient overexpression lysate of MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 3 | 100 ug | | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.