Mouse Anti-Chicken c-Kit-PE
Référence 8380-09
Conditionnement : 0.1mg
Marque : Southern Biotech
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| Clone | kit2c75 |
|---|---|
| Isotype | Mouse (BALB/c) IgG2aκ |
| Isotype Control | Mouse IgG2a-PE (HOPC-1) |
| Specificity | Chicken c-Kit |
| Alternative Names | CD117 |
| Description | c-Kit is a 145 kDa transmembrane receptor-type protein tyrosine kinase encoded by the c-Kit proto-oncogene and is the receptor for stem cell factor (SCF). c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis, and adhesion. The amino acid sequence of chicken c-kit shows 63% identity to mouse c-Kit and exhibits similar expression patterns in RNA blot analysis suggesting similar biological roles. |
| Immunogen | Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA) |
| Conjugate | PE (R-phycoerythrin) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
| Applications | Flow Cytometry – Quality tested 1-7 |
| RRID Number | AB_2796532 |
| Gene ID | 378783 (Chicken) |
| Gene ID Symbol | KIT (Chicken) |
| Gene ID Aliases | SCFR |
| UniProt ID | Q08156 (Chicken |
| UniProt Name | KIT_CHICK (Chicken) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 1. Vainio O, Dunon D, Aïssi F, Dangy J, McNagny KM, Imhof BA. HEMCAM, an adhesion molecule expressed by c-kit+ hemopoietic progenitors. J Cell Biol. 1996;135:1655-68. (Immunogen, FC)
- 2. Lampisuo M, Katevuo K, Lassila O. Antigenic phenotype of early intra-embryonic lymphoid progenitors in the chicken. Scand J Immunol. 1998;48:52-8. (FC)
- 3. Dunon D, Alliolo N, Vainio O, Ody C, Imhof BA. Quantification of T-cell progenitors during ontogeny: thymus colonization depends on blood delivery of progenitors. Blood. 1999;93:2234-43. (FC)
- 4. Ody C, Vaigot P, Quéré P, Imhof BA, Corbel C. Glycoprotein IIb-IIIa is expressed on avian multilineage hematopoietic progenitor cells. Blood. 1999;93:2898-906. (FC)
- 5. Lampisuo M, Liippo J, Vainio O, McNagny KM, Kulmala J, Lassila O. Characterization of prethymic progenitors within the chicken embryo. Int Immunol. 1999;11:63-9. (FC)
- 6. Schulte CE, von Lindern M, Steinlein P, Beug H, Wiedemann LM. MLL-ENL cooperates with SCF to transform primary avian multipotent cells. EMBO J. 2002;21:4297-306. (FC)
- 7. Trefil P, Bakst MR, Yan H, Hejnar J, Kalina J, Mucksová J. Restoration of spermatogenesis after transplantation of c-Kit positive testicular cells in the fowl. Theriogenology. 2010;74:1670-6. (FC)