Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.
 
> Mouse Anti-Human CD19-AF647

Mouse Anti-Human CD19-AF647

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Référence 9340-31

Conditionnement : 100tests

Marque : Southern Biotech

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Product Specifications

More Information
Clone SJ25-C1
Isotype Mouse (BALB/c) IgG1κ
Isotype Control Mouse IgG1-AF647 (15H6)
Specificity Human CD19
Alternative Names B4, B-lymphocyte antigen, Leu-12
Description CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).
Immunogen NALM-1 and NALM-16 leukemia cell line
Conjugate AF647 (Alexa Fluor® 647)
Buffer Formulation Phosphate buffered saline containing < 0.1% sodium azide
Clonality Monoclonal
Concentration Lot specific
Volume 1.0 mL
Recommended Storage 2-8°C; Avoid exposure to light
Trademark Information Alexa Fluor® is a registered trademark of Thermo Fisher Scientific, Inc. or its subsidiaries
Applications Flow Cytometry – Quality tested 5-13
Immunohistochemistry-Frozen Sections – Reported in literature 1
Immunoprecipitation – Reported in literature 2
Blocking – Reported in literature 3,4

RRID Number AB_2796753
Gene ID 930 (Human)
Gene ID Symbol CD19 (Human)
Gene ID Aliases B4; CVID3
UniProt ID P15391 (Human
UniProt Name CD19_HUMAN (Human)

Documentation

Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup

Enter the Catalog Number and Lot Number for the Certificate of Analysis you wish to view

Other Conjugates and Formulations

UNLB BIOT PE/TXRD SPRD LE/AF CY5 PE/CY5.5 PE/CY7 APC/CY5.5 APC/CY7 PACBLU AF700 AF488 FITC PE APC

Citations

  1. 1. Vuyyuru R, Liu H, Manser T, Alugupalli KR. Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever. Proc Natl Acad Sci USA. 2011;108:20707-12. (IHC-FS)
  2. 2. Nadler LM. B cell/leukemia panel workshop: summary and comments. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, editors. Leukocyte Typing II: Human B Lymphocytes. New York: Springer-Verlag; 1986. p. 3-43. (IP)
  3. 3. Moldenhauer G, Dörken B, Schwartz R, Pezzutto A, Knops J, Hämmerling GJ. Analysis of ten B lymphocyte-specific workshop monoclonal antibodies. In: Reinherz EL, Haynes BF, Nadler LM, Bernstein ID, editors. Leukocyte Typing II: Human B Lymphocytes. New York: Springer-Verlag; 1986. p. 61-7. (Block)
  4. 4. de Rie MA, Terpstra FG, van Lier RA, von dem Borne AE, Miedema F. Identification of functional epitopes on workshop-defined B-cell membrane molecules. In: McMichael AJ, Beverley PC, Cobbold S, Crumpton MJ, Gilks W, Gotch FM, et al, editors. Leukocyte Typing III: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1987. p. 402-5. (Block)
  5. 5. Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, Burmester GR, et al. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol. 2000;165:5970-9. (FC)
  6. 6. Odendahl M, Keitzer R, Wahn U, Hiepe F, Radbruch A, Dörner T, et al. Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus. Ann Rheum Dis. 2003;62:851-8. (FC)
  7. 7. Henneken M, Dörner T, Burmester G, Berek C. Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther. 2005;7:R1001-13. (FC)
  8. 8. Shankar SP, Petrie TA, García AJ, Babensee JE. Dendritic cell responses to self-assembled monolayers of defined chemistries. J Biomed Mater Res A. 2010;92:1487-99. (FC)
  9. 9. Shankar SP, Babensee JE. Comparative characterization of cultures of primary human macrophages or dendritic cells relevant to biomaterial studies. J Biomed Mater Res A. 2010;92:791-800. (FC)
  10. 10. Chung BH, Kim KW, Sun IO, Choi SR, Park HS, Jeon EJ, et al. Increased interleukin-17 producing effector memory T cells in the end-stage renal disease patients. Immunol Lett. 2011;141:181-9. (FC)
  11. 11. Kim KW, Chung BH, Jeon EJ, Kim B, Choi BS, Park CW, et al. B cell-associated immune profiles in patients with end-stage renal disease (ESRD). Exp Mol Med. 2012;44:465-72. (FC)
  12. 12. Kim HY, Cho M, Jhun JY, Byun JK, Kim E, Yim YB, et al. The imbalance of T helper 17/regulatory T cells and memory B cells during the early post-transplantation period in peripheral blood of living donor liver transplantation recipients. Immunology. 2013;138:124-33. (FC)
  13. 13. Chung BH, Kim KW, Yu JH, Kim B, Choi BS, Park CW, et al. Decrease of immature B cell and interleukin-10 during early-post-transplant period in renal transplant recipients under tacrolimus based immunosuppression. Transpl Immunol. 2014;30:159-67. (FC)