General Info
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.073ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This SGPP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | Sgpp2 |
| Gene ID: | 433323 |
| Uniprot ID: | SGPP2_MOUSE |
| Sample Type: | tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Highly expressed in pancreatic islets. Expressed in lung, small interstince, colon, kideny and brain. |
| Post Translational Modifications | |
| Function | Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (Probable). Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation. |
| Protein Name | Sphingosine-1-Phosphate Phosphatase 2Sppase2Spp2Sphingosine-1-Phosphatase 2 |
| Database Links | Reactome: R-MMU-1660661 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Sphingosine-1-Phosphate Phosphatase 2 ELISA kitSppase2 ELISA kitSpp2 ELISA kitSphingosine-1-Phosphatase 2 ELISA kitSgpp2 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance