MTAP monoclonal antibody (M01), clone 2G4

Référence H00004507-M01

Conditionnement : 100ug

Marque : Abnova

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  • Specifications

    Product Description

    Mouse monoclonal antibody raised against a full length recombinant MTAP.MAB,monoclonal Ab,monoclonal antibody

    Immunogen

    MTAP (AAH18625, 1 a.a. ~ 154 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCILLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDSHVRRACFPFTFHHDCFQRPPQKPSRSHCVSCATCRTMS

    Host

    Mouse

    Reactivity

    Human, Mouse, Rat

    Interspecies Antigen Sequence

    Mouse (89)

    Isotype

    IgG1 Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (42.68 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Cell lysate)

    MTAP monoclonal antibody (M01), clone 2G4 Western Blot analysis of MTAP expression in HeLa ( Cat # L013V1 ).

    Western Blot (Cell lysate)

    MTAP monoclonal antibody (M01), clone 2G4. Western Blot analysis of MTAP expression in NIH/3T3 ( Cat # L018V1 ).

    Western Blot (Cell lysate)

    MTAP monoclonal antibody (M01), clone 2G4. Western Blot analysis of MTAP expression in PC-12 ( Cat # L012V1 ).

    Western Blot (Cell lysate)

    MTAP monoclonal antibody (M01), clone 2G4. Western Blot analysis of MTAP expression in Raw 264.7 ( Cat # L024V1 ).

    Western Blot (Recombinant protein)

    Sandwich ELISA (Recombinant protein)

    Detection limit for recombinant GST tagged MTAP is approximately 0.3ng/ml as a capture antibody.

    ELISA

    Immunofluorescence

    Immunofluorescence of monoclonal antibody to MTAP on HeLa cell. [antibody concentration 10 ug/ml]
  • Gene Info class="font-18 semiblod">Entrez GeneID 4507

    GeneBank Accession#

    BC018625

    Protein Accession#

    AAH18625

    Gene Name

    MTAP

    Gene Alias

    MSAP, c86fus

    Gene Description

    methylthioadenosine phosphorylase

    Omim ID

    156540

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq

    Other Designations

    5'-methylthioadenosine phosphorylase|MeSAdo phosphorylase|OTTHUMP00000021152

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    Référence
    Description
    Cond.
    Prix HT
    9200-01
     0.5mg