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> N-Glycolylneuraminic acid

N-Glycolylneuraminic acid

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Référence M19972-10mg

Conditionnement : 10mg

Marque : AbMole Bioscience

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N-Glycolylneuraminic acid Structure
Synonym:

NeuGc; GcNeu

Quality Control & Documentation
Biological Activity

N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).

Chemical Information
Molecular Weight 325.27
Formula C11H19NO10
CAS Number 1113-83-3
Solubility (25°C) Water ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cindy M Spruit, et al. J Virol. N-Glycolylneuraminic Acid Binding of Avian and Equine H7 Influenza A Viruses

[2] Renato Mastrangeli, et al. Trends Pharmacol Sci. Current views on N-glycolylneuraminic acid in therapeutic recombinant proteins

[3] Sharon Yehuda, et al. Front Immunol. Glycosylated Biotherapeutics: Immunological Effects of N-Glycolylneuraminic Acid

[4] Andrea Perota, et al. Front Immunol. N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH)

[5] Anoopjit Singh Kooner, et al. Front Immunol. Synthesis of N-Glycolylneuraminic Acid (Neu5Gc) and Its Glycosides