NGAL (LCN2) Human Gene Knockout Kit (CRISPR)
Référence KN207685BN
Conditionnement : 1kit
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NGAL (LCN2) Human Gene Knockout Kit (CRISPR)
SKU
KN207685BN
LCN2 - human gene knockout kit via CRISPR, HDR mediated
4 Weeks*
| Product Data | |
| Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
|---|---|
| Vector | mBFP-Neo |
| Target Symbol | NGAL |
| Locus ID | 3934 |
| Components | KN207685G1, NGAL gRNA vector 1 in pCas-Guide CRISPR vector KN207685G2, NGAL gRNA vector 2 in pCas-Guide CRISPR vector KN207685BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_005564, N79823 |
| UniProt ID | P80188 |
| Synonyms | 24p3; MSFI; NGAL |
| Summary | This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| GA102668 | LCN2 CRISPRa kit - CRISPR gene activation of human lipocalin 2 | 1 kit | | |
| KN207685 | LCN2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN207685LP | LCN2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN207685RB | LCN2 - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
| KN407685 | LCN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.