PRMT5 Human shRNA Plasmid Kit (Locus ID 10419)

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Conditionnement : 1kit

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PRMT5 Human shRNA Plasmid Kit (Locus ID 10419)

Specifications
Product Data
Locus ID 10419
Synonyms HRMT1L5; HSL7; IBP72; JBP1; SKB1; SKB1Hs
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components PRMT5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10419). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001039619, NM_001282953, NM_001282954, NM_001282955, NM_001282956, NM_006109, NM_006109.1, NM_006109.2, NM_006109.3, NM_006109.4, NM_001039619.1, NM_001039619.2, NM_001282956.1, NM_001282954.1, NM_001282953.1, NM_001282955.1, BC025979, BC025979.2, BC005820, NM_001282956.2, NM_001039619.3, NM_001282954.2, NM_001282953.2, NM_006109.5, NM_001282955.2
UniProt ID O14744
Summary This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact tech@clinisciences.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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