SLC6A16 (Orphan Sodium- and Chloride-Dependent Neurotransmitter Transporter NTT5, Solute Carrier Family 6 Member 16, NTT5)

NTT5, also known as SLC6A16 (solute carrier family 6 member 16), is a 736aa multi-pass membrane protein that belongs to the sodium: neurotransmitter symporter (SNF) family and the SLC6A16 subfamily. NTT5 is highly expressed in peripheral tissues, particularly in testis, pancreas and prostate. Showing structural characteristics of a Na+- and Cl-- dependent neurotransmitter transporter, NTT5 consists of twelve transmembrane domains, intracellular N and C termini and large extracellular loops containing multiple N-glycosylation sites. The gene that encodes NTT5 consists of approximately 35,586 bases and maps to human chromosome 19q13. Chromosome 19 consists of over 63 million bases, houses approximately 1400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).||Applications: |Suitable for use in Western Blot. Other applications not tested.||Recommended Dilution:|Western Blot: 1:500-1:1000|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.