SUMO2, Xenopus, NT (sumo2-a, smt3h2, Small ubiquitin-related modifier 2-A) (FITC)

Référence 042478-FITC-200ul

Conditionnement : 200ul

Marque : US Biological

Demander plus d'informations

Contactez votre distributeur local :


Téléphone : +1 850 650 7790


042478-FITC SUMO2, Xenopus, NT (sumo2-a, smt3h2, Small ubiquitin-related modifier 2-A) (FITC) discontinued

Clone Type
Polyclonal
Host
rabbit
Source
Xenopus
Swiss Prot
Q7ZTK7
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA WB
Gene #
sumo2-a
Shipping Temp
Blue Ice
Storage Temp
-20°C

SUMO2 is a ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. SUMO2 does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. This protein plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS isoforms 1-4.||Applications:|Suitable for use in Western Blot, FLISA||Recommended Dilution:|FLISA: 1:1,000|Western Blot: 1:100-500||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: Xenopus|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).|Purity: Purified by Protein A affinity chromatography.|Immunogen: Xenopus SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Xenopus SUMO2.|Specificity: X||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Xenopus SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of Xenopus SUMO2.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A affinity chromatography.
Specificity
X
References
Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review.|Hochstrasser M. Cell. 2001 107(1):5-8. Review.|Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8.|Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review.|Keane,M.M., et al., Oncogene 18 (22), 3365-3375 (1999)