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> Taxol [33069-62-4]

Taxol [33069-62-4]

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Taxol | Microtubule stabilizing agent

CAS:
33069-62-4
Catalog Number:
10-2095
Activity:
Microtubule stabilizing agent
Alternate Names:
Paclitaxel
Molecular Weight:
853.91
Molecular Formula:
C47H51NO14
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

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5 mg$30.00
25 mg$65.00
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Taxol (33069-62-4) is a clinically useful cancer chemotherapeutic agent for the treatment of breast, non-small cell lung and ovarian cancer.1 Taxol acts as a promoter of tubulin polymerization and stabilizes microtubules in vitro and in vivo resulting in arrest of cells in the G2 and M phase of the cell cycle.2

References/Citations:

1) Rowinsky and Donehower (1995) Drug Therapy: Paclitaxel(Taxol); N. Engl. J. Med., 332 1004
2) Schiff and Horwitz (1980) Taxol stabilizes microtubules in mouse fibroblast cells; Proc. Nat. Acad. Sci.USA, 77 1561

CAS:
33069-62-4
Catalog Number:
10-2095
Activity:
Microtubule stabilizing agent
Alternate Names:
Paclitaxel
Molecular Weight:
853.91
Molecular Formula:
C47H51NO14
Solubility:
Soluble in DMSO (up to 50 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

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Product Data Sheet:

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Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a restocking/refund fee

Taxol (33069-62-4) is a clinically useful cancer chemotherapeutic agent for the treatment of breast, non-small cell lung and ovarian cancer.1 Taxol acts as a promoter of tubulin polymerization and stabilizes microtubules in vitro and in vivo resulting in arrest of cells in the G2 and M phase of the cell cycle.2

References/Citations:

1) Rowinsky and Donehower (1995) Drug Therapy: Paclitaxel(Taxol); N. Engl. J. Med., 332 1004
2) Schiff and Horwitz (1980) Taxol stabilizes microtubules in mouse fibroblast cells; Proc. Nat. Acad. Sci.USA, 77 1561