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QC Test

  • Specification

    Product Description

    Human UPK1B partial ORF ( NP_008883, 131 a.a. - 228 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    NNSPPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCVMNNLKEPLNLEACKLGVPGFYHNQGCYELISGPMNR

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.52

    Interspecies Antigen Sequence

    Mouse (90); Rat (86)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — UPK1B

    Entrez GeneID

    7348

    GeneBank Accession#

    NM_006952

    Protein Accession#

    NP_008883

    Gene Name

    UPK1B

    Gene Alias

    TSPAN20, UPIB, UPK1

    Gene Description

    uroplakin 1B

    Omim ID

    602380

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq

    Other Designations

    tetraspan

  • Interactome